- Sono ormai disponibili numerosi dati in letteratura che mostrano un’associazione tra psoriasi e numerose comorbilità, sia negli adulti che nei bambini.
- La presente revisione fornisce una miglior comprensione sui rischi presenti e futuri della psoriasi non trattata e non controllata nei bambini, ma anche sui benefici e i rischi dei nuovi trattamenti disponibili.
Purpose of review
Psoriasis is a multifactorial, chronic, inflammatory skin disease that may represent a therapeutic challenge in children. This review aims to provide a framework for the management of pediatric psoriasis, emphasizing in new insights and considerations for management. It will focus on new disease associations and innovative treatment modalities that challenge current approach of psoriasis in children.
There is an increasing body of literature both in adults and in children linking psoriasis with different comorbidities. This new evidence points to the need of addressing psoriasis as a systemic disease and suggests the need for screening and creating awareness of possible associations. In a similar manner, newer medications are also being investigated in children. Recent publications report on the efficacy and safety of biologics for psoriasis in pediatric patients.
The review provides better understanding of present and future risks of untreated and uncontrolled psoriasis in children and at the same time the benefits and risks of new treatments available.